Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573808 | 0.75 | CYP3A4 (0.57) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Fumaric Acid SCHEMBL8304290 | 0.71 | CYP3A4 (0.45) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2635660 | 0.66 | EGFR (0.63) | KMT2ACYP2C9MAPTALDH1A1POLB | |
| SCHEMBL11214735 | 0.64 | ALDH1A1 (0.40) | ALDH1A1LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL17131912 | 0.64 | MAPT (1.00) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8673747 | 0.63 | NAMPT (0.45) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL17137972 | 0.63 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAHPGDHTT | |
| SCHEMBL916728 | 0.62 | POLB (0.73) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL10784324 | 0.61 | ALDH1A1 (0.40) | MEN1KMT2ACYP3A4CYP2C19MAPT | |
| SCHEMBL307790 | 0.61 | MEN1 (0.62) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362548-A | Herbicidal and plant-growth-regulating N-substituted-N-(2,5-dialkylpyrrol-1-yl) haloacetamides | CHEVRON RESEARCH COMPANY (US) | 1982-12-07 | — | — | US | disclosed |
| US-4282028-A | Herbicidal and plant-growth-regulating N-substituted-N-(2,5-dialkylpyrrol-1-yl) haloacetamides | CHEVRON RESEARCH COMPANY (US) | 1981-08-04 | — | — | US | disclosed |