Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11270222 | 0.98 | HTR2A (0.38) | HTR2AHTR2CHTR2BCA1CA2 | |
| SCHEMBL11275332 | 0.83 | MAPT (0.36) | HTR2CCA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL11273290 | 0.82 | MEN1 (0.37) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11273176 | 0.81 | MAPT (0.35) | HTR2CCA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL11276985 | 0.81 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL11262097 | 0.81 | HTR2C (0.39) | HTR2AHTR2CHTR2BCA1CA2 | |
| SCHEMBL11263563 | 0.81 | HTR2C (0.39) | HTR2AHTR2CCA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL11269902 | 0.80 | HTR2C (0.38) | HTR2AHTR2CHTR2BCA1CA2 | |
| Hydrochloric Acid SCHEMBL11267162 | 0.80 | HTR2C (0.38) | HTR2AHTR2CCA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL11275784 | 0.80 | CA1 (0.33) | CA1CA2MAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |