Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 8/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11267162 | 0.98 | HTR2C (0.38) | HTR2CHTR2ACA1CA2CHRNB2 | |
| SCHEMBL11275332 | 0.83 | MAPT (0.36) | HTR2CCA1CA2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL11273176 | 0.81 | MAPT (0.35) | HTR2CCA1CA2CHRNB2CHRNA4 | |
| SCHEMBL11260229 | 0.81 | HTR2A (0.39) | HTR2CHTR2ACA1CA2MAPT | |
| SCHEMBL11276985 | 0.81 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL11262097 | 0.81 | HTR2C (0.39) | HTR2CHTR2ACA1CA2CHRNB2 | |
| SCHEMBL11273824 | 0.81 | HTR2A (0.43) | HTR2CHTR2ACA1CA2CHRNB2 | |
| Hydrochloric Acid SCHEMBL11269902 | 0.80 | HTR2C (0.38) | HTR2CHTR2ACA1CA2CHRNB2 | |
| Hydrochloric Acid SCHEMBL11275784 | 0.80 | CA1 (0.33) | CA1CA2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11270222 | 0.80 | HTR2A (0.38) | HTR2CHTR2ACA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |