Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 4/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264341 | 0.90 | TSHR (0.39) | TSHRELANEITGALITGB2ICAM1 | |
| SCHEMBL11259364 | 0.79 | TSHR (0.47) | TSHRELANEITGALITGB2ICAM1 | |
| SCHEMBL11722683 | 0.64 | ITGAL (0.49) | TSHRELANEITGALITGB2ICAM1 | |
| SCHEMBL11257965 | 0.64 | TSHR (0.46) | TSHRELANEITGALITGB2ICAM1 | |
| SCHEMBL4839880 | 0.63 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL11721669 | 0.60 | ITGAL (0.45) | TSHRELANEITGALITGB2ICAM1 | |
| SCHEMBL10691960 | 0.60 | ELANE (0.42) | ELANEALDH1A1PGRKMT2A | |
| SCHEMBL11719337 | 0.60 | ITGAL (0.62) | TSHRELANEITGALITGB2ICAM1 | |
| Procymidone SCHEMBL23093 | 0.59 | TSHR (1.00) | TSHRELANEITGALITGB2ICAM1 | |
| SCHEMBL7665397 | 0.59 | ITGAL (0.41) | TSHRITGALITGB2ICAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006633-B1 | 6-(3,5-DICHLOROPHENYL)PERHYDROIMIDAZO(5,1-B)THIAZOLE DERIVATIVES, ANTIFUNGAL COMPOSITIONS AND A METHOD OF CONTROLLING FUNGAL INFECTIONS IN PLANTS | MITSUBISHI KASEI CORPORATION (JP) | 1982-02-03 | — | — | EP | disclosed |
| US-4229461-A | Fungicidal 6-(3,5-dichlorophenyl)perhydroimidazo[5,1-b]thiazole derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1980-10-21 | — | — | US | disclosed |