⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12011138 | 0.92 | — | — | |
| SCHEMBL12011137 | 0.92 | — | — | |
| SCHEMBL4146119 | 0.92 | — | — | |
| SCHEMBL16588572 | 0.80 | — | — | |
| SCHEMBL25277259 | 0.79 | — | — | |
| SCHEMBL1054243 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL21640431 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL10876938 | 0.78 | — | — | |
| SCHEMBL23192858 | 0.78 | — | — | |
| SCHEMBL16369916 | 0.76 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4240985-A | FROM 2,2-DIALKYLTETRAHYDROPYRANS WITH ACID CATALYST | ETHYL CORPORATION (US) | 1980-12-23 | — | — | US | claimed |
| EP-2271622-B1 | Heteroaryl derivatives as CFTR Modulators | VERTEX PHARMA (US) | 2017-10-04 | — | — | EP | disclosed |
| US-9296758-B2 | 2-quinolinyl-acetic acid derivatives as HIV antiviral compounds | GILEAD SCIENCES, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-8574814-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, and actinic ray-sensitive or radiation-sensitive film and pattern forming method using the composition | FUJIFILM CORPORATION (JP) | 2013-11-05 | — | — | US | disclosed |
| US-8574814-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, and actinic ray-sensitive or radiation-sensitive film and pattern forming method using the composition | FUJIFILM CORPORATION (JP) | 2013-11-05 | — | — | US | disclosed |
| US-20130210801-A1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-20130004888-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20130004888-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2013-01-03 | — | — | US | disclosed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4254038-A | ODORS; PERFUMES; FOR COMPLEXING SOLVENTS | ETHYL CORPORATION (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254037-A | FOR PERFUMES, ODORANTS, COMPLEXING SOLVENTS | ETHYL CORPORATION (US) | 1981-03-03 | — | — | US | disclosed |
| US-4240985-A | FROM 2,2-DIALKYLTETRAHYDROPYRANS WITH ACID CATALYST | ETHYL CORPORATION (US) | 1980-12-23 | — | — | US | disclosed |
| US-4212812-A | TREATING AN ALKENOL WITH A STRONG ACID TO EFFECT CYCLIZATION | ETHYL CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |