SCHEMBL11260751

SCHEMBL11260751

O=C(Cl)NC1(Cl)CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11260754 0.78 CYP2C19 (0.32)
SCHEMBL27991208 0.78 HTT (0.40) MEN1POLBKMT2A
SCHEMBL16935128 0.70 HDAC3 (0.33) MEN1POLBKMT2A
SCHEMBL11688161 0.70
SCHEMBL6565141 0.69 CETP (0.34) MEN1POLBKMT2A
SCHEMBL10785352 0.67 P2RX7 (0.36)
SCHEMBL11825332 0.65 CYP2C19 (0.32)
SCHEMBL2002432 0.65 CYP2C19 (0.32)
SCHEMBL15419129 0.65
SCHEMBL11234496 0.63 USP2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314948-A Preparation of mixtures of 1-monohalogenated isocyanates and 1,2-unsaturated isocyanates BASF AKTIENGESELLSCHAFT (DE) 1982-02-09 US disclosed