Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263977 | 0.93 | CYP19A1 (0.41) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11267712 | 0.90 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2POLBQPCT | |
| SCHEMBL11257567 | 0.90 | HMOX1 (0.43) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11260418 | 0.90 | QPCT (0.39) | CYP19A1TBXAS1CYP11B1CYP11B2QPCT | |
| SCHEMBL11268531 | 0.89 | CYP19A1 (0.43) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11255906 | 0.89 | CYP2A6 (0.46) | CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11269446 | 0.89 | CYP1A2 (0.41) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11264326 | 0.89 | HMOX1 (0.46) | CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11267511 | 0.88 | CYP11B1 (0.44) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11252522 | 0.88 | CYP19A1 (0.38) | CYP19A1HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |