Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247112 | 0.82 | LDHA (0.58) | SMN1; SMN2HTTGAAALOX15MAPK1 | |
| SCHEMBL28698713 | 0.77 | HPGD (0.45) | SMN1; SMN2HTTGAANR2F2GALR3 | |
| SCHEMBL29898303 | 0.77 | HPGD (0.45) | SMN1; SMN2HTTGAANR2F2GALR3 | |
| SCHEMBL28698711 | 0.77 | HPGD (0.45) | SMN1; SMN2HTTGAANR2F2GALR3 | |
| SCHEMBL11246532 | 0.77 | EGFR (0.51) | SMN1; SMN2HTTGAAALOX15MAPK1 | |
| SCHEMBL11251547 | 0.76 | GALR3 (0.51) | SMN1; SMN2HTTGAAALOX15MAPK1 | |
| SCHEMBL11254607 | 0.74 | LDHA (0.64) | SMN1; SMN2HTTGAAMAPK1HSD17B10 | |
| SCHEMBL28689151 | 0.73 | EGFR (0.42) | SMN1; SMN2HTTGAAALOX15MAPK1 | |
| SCHEMBL28689152 | 0.73 | EGFR (0.42) | SMN1; SMN2HTTGAAALOX15MAPK1 | |
| SCHEMBL29898291 | 0.73 | EGFR (0.42) | SMN1; SMN2HTTGAAALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |