Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265755 | 0.89 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11260909 | 0.86 | CYP11B1 (0.44) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11266636 | 0.84 | MAPK1 (0.40) | KMT2AMEN1ALDH1A1LMNAPRKCI | |
| SCHEMBL11271243 | 0.84 | QPCT (0.44) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11265565 | 0.83 | CYP11B1 (0.41) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11260803 | 0.81 | CYP11B1 (0.46) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11263977 | 0.81 | CYP19A1 (0.41) | CYP11B1CYP11B2KMT2AALDH1A1KDM4E | |
| SCHEMBL10785066 | 0.81 | TBXAS1 (0.44) | KMT2AKDM4ELMNAPRKCIHSD17B10 | |
| SCHEMBL11257083 | 0.80 | POLB (0.43) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL10780679 | 0.79 | TBXAS1 (0.50) | KMT2AALDH1A1KDM4ELMNAPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |