Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.67 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633283 | 0.86 | CES1 (0.67) | CES1SRCTDP1CYP3A4MAPT | |
| SCHEMBL8780870 | 0.84 | CES1 (0.64) | CES1SRCTDP1MLYCDTSHR | |
| SCHEMBL27459649 | 0.82 | CES1 (0.61) | CES1SRCTDP1MLYCDTSHR | |
| SCHEMBL9017510 | 0.82 | CES1 (0.61) | CES1SRCTDP1ALOX15MLYCD | |
| SCHEMBL5158726 | 0.82 | CES1 (0.61) | CES1SRCTDP1MLYCDTSHR | |
| SCHEMBL3134419 | 0.81 | CES1 (0.60) | CES1SRCTDP1CYP3A4MAPT | |
| SCHEMBL13662398 | 0.80 | CES1 (0.59) | CES1SRCTDP1ALOX15MLYCD | |
| SCHEMBL7907262 | 0.80 | CES1 (0.73) | CES1SRCTDP1MAPK1CYP3A4 | |
| SCHEMBL226691 | 0.80 | CES1 (0.58) | CES1SRCTDP1MAPK1CYP3A4 | |
| SCHEMBL21109870 | 0.80 | CES1 (0.58) | CES1SRCTDP1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362891-A | ANTIINFLAMMATORY AGENTS, DEHYDRATION | GLAXO GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |