SCHEMBL7907262

SCHEMBL7907262

O=C(c1ccccc1)C(F)(F)C(=O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.73
CES2 O00748 4/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
SRC P12931 1/20 0.47
TDP1 Q9NUW8 4/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
HSD17B10 Q99714 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA9 Q16790 2/20 0.46
POLB P06746 1/20 0.46
PARP1 P09874 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6171178 0.88 CES1 (0.64) CES1CES2TSHRALDH1A1DAO
SCHEMBL524182 0.86 CES1 (0.61) CES1CES2TSHRALDH1A1DAO
Benzene SCHEMBL27672585 0.84 CES1 (1.00) CES1CES2TSHRALDH1A1DAO
SCHEMBL33083 0.84 CES1 (1.00) CES1CES2TSHRALDH1A1DAO
SCHEMBL583437 0.83 CES1 (0.57) CES1CES2TSHRALDH1A1DAO
SCHEMBL29393401 0.82 CES1 (0.95) CES1CES2TSHRALDH1A1DAO
SCHEMBL29035921 0.82 CES1 (0.70) CES1CES2TSHRALDH1A1DAO
Fluoride SCHEMBL27824066 0.82 CES1 (0.95) CES1CES2TSHRALDH1A1DAO
SCHEMBL31083855 0.82 CES1 (0.95) CES1CES2TSHRALDH1A1DAO
SCHEMBL1743416 0.82 CES1 (0.70) CES1CES2TSHRALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942459-B Method for synthesizing 3-difluoromethyl-3-acrylonitrile compounds 南京理工大学 2022-06-24 CN disclosed
CN-114307890-A Bamboo capsule and preparation method and application thereof 中国林业科学研究院木材工业研究所 2022-04-12 CN disclosed
US-6174628-B1 ELECTROLYTE HAS HIGH POLARITY, HIGH RESISTANCE TO OXIDATION AND FLAME RETARDANCE, AND THUS POSSESSES EXCELLENT CHARACTERISTICS AS THE ELECTROLYTE FOR ELECTRIC ENERGY GENERATORS DAIKIN INDUSTRIES, LTD. (JP) 2001-01-16 US disclosed
EP-0948073-A1 ELECTROLYTIC SOLUTION AND DEVICE FOR GENERATING ELECTRIC ENERGY THEREWITH Daikin Industries, Ltd. (JP) 1999-10-06 EP disclosed