SCHEMBL11261557

SCHEMBL11261557

CCCCc1cc(N2CCOCC2)ccc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGMN Q99538 4/20 0.55
MAPT P10636 6/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 4/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 2/20 0.41
RAD52 P43351 1/20 0.41
TP53 P04637 2/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
USP2 O75604 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
PRKDC P78527 1/20 0.40
AGXT P21549 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15692557 0.91 LGMN (0.58) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL16640695 0.90 GAA (0.50) LGMNMAPTSMN1; SMN2ALDH1A1MEN1
SCHEMBL15358733 0.87 MAPT (0.51) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL18051450 0.85 LGMN (0.61) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL28105317 0.84 MAPT (0.46) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL10061539 0.84 LGMN (0.59) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL17264107 0.83 LGMN (0.41) LGMNMAPTALDH1A1MEN1KMT2A
Formamide SCHEMBL28230389 0.81 PRKDC (0.43) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL13724622 0.81 LGMN (0.56) LGMNMAPTSMN1; SMN2NPC1RAB9A
SCHEMBL17265645 0.80 GAA (0.53) LGMNMAPTSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed