Sugi Predict

Sugi Predict / Targets / LGMN

LGMN

Legumain · Q99538 · LGMN on Sugi Atlas →

6,455 patent compounds predicted against LGMN, 2,976 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2534042 SCHEMBL2534042 0.43 9/20
SCHEMBL1574146 SCHEMBL1574146 0.36 9/20
SCHEMBL3540354 SCHEMBL3540354 0.77 6/20
SCHEMBL3545551 SCHEMBL3545551 0.58 6/20
SCHEMBL3538623 SCHEMBL3538623 0.54 6/20
SCHEMBL3958578 SCHEMBL3958578 0.53 6/20
SCHEMBL3536844 SCHEMBL3536844 0.87 5/20
SCHEMBL3533602 SCHEMBL3533602 0.87 5/20
SCHEMBL3538453 SCHEMBL3538453 0.70 5/20
SCHEMBL1853113 SCHEMBL1853113 0.67 5/20
SCHEMBL2060797 SCHEMBL2060797 0.64 5/20
Trifluoroacetic Acid Trifluoroacetic Acid (SCHEMBL3539482) 0.52 5/20
SCHEMBL3966409 SCHEMBL3966409 0.51 5/20
SCHEMBL3537508 SCHEMBL3537508 0.49 5/20
SCHEMBL2711166 SCHEMBL2711166 0.74 4/20
SCHEMBL904452 SCHEMBL904452 0.73 4/20
SCHEMBL3538700 SCHEMBL3538700 0.69 4/20
SCHEMBL178686 SCHEMBL178686 0.68 4/20
SCHEMBL78755 SCHEMBL78755 0.67 4/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL2951905) 0.65 4/20

Clinical trials — most relevant to LGMN by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparison of Two Concomitant Administration of RT With Cisplatin in Standard Infusion or Fractional Infusion PHASE2COMPLETED
Influence of Statins in Artery Aneurysms nanUNKNOWN
LRP1 and Colon Cancer nanUNKNOWN
Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer nanCOMPLETED
Pharmacokinetics of Low Molecular Weight Heparin in Cancer Patients nanCOMPLETED
The Natural History of Alpha-Mannosidosis nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery nanCOMPLETED
Sensitivity and Specificity of NGAL in an Emergency Room Population nanCOMPLETED
Serum NGAL IN Patients With Multiple Myeloma nanUNKNOWN
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED
Biomarkers of Lichen Sclerosus nanUNKNOWN
Identification of Biomarkers for Early Detection of Pancreatic Cancer nanCOMPLETED
Screening of Lysosomal Storage Disorders Diseases in Minority Groups nanUNKNOWN
NAG-excretion During Cardiopulmonary Bypass nanCOMPLETED
Genome Environment Microbiome and Metabolome in Autism Study nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects nanAVAILABLE
Registry Gangliosidoses nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) nanCOMPLETED
Proteomic Profiling for Congenital Diaphragmatic Hernia nanUNKNOWN
Acute Rhabdomyolysis and Muscle Pain Associated With Mutations in the LPIN1 Gene - A Retrospective Study Describing the Safety and Efficacy of Hydroxychloroquine Sulfate Given on a Compassionate Basis to Patients Suffering From Lipin-1 Deficiency nanWITHDRAWN
Genetic Variants in Linear Localized Scleroderma nanCOMPLETED
Screening and Therapeutic Monitoring of Multiple Myeloma by MALDI-TOF MS Analysis nanRECRUITING
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
Correlation and Clinical Utility of Urinary Biomarker in Membranous Glomerulonephritis nanUNKNOWN
Proteomic Profiling to Reveal Novel Prognostic Markers for Neurological Outcome Following Resuscitation nanCOMPLETED
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a LGMN binder may also engage these)

ProteinNameSimilarity
Q4R4T8 — 1.000 Q4R4T8 →
Q9R0J8 — 1.000 Q9R0J8 →
O89017 — 1.000 O89017 →
Q5R5D9 — 1.000 Q5R5D9 →
Q95M12 — 0.998 Q95M12 →
P49046 — 0.992 P49046 →
O24326 — 0.991 O24326 →
O24325 — 0.991 O24325 →
P49043 — 0.991 P49043 →
P49045 — 0.990 P49045 →
P09841 — 0.990 P09841 →
Q39119 — 0.989 Q39119 →
P42665 — 0.989 P42665 →
P49047 — 0.989 P49047 →
P49048 — 0.988 P49048 →
P49042 — 0.987 P49042 →
Q9LJX8 — 0.987 Q9LJX8 →
P49044 — 0.987 P49044 →
Q39044 — 0.986 Q39044 →
B8ASK4 — 0.986 B8ASK4 →
Q84LM2 — 0.985 Q84LM2 →
Q8GS39 — 0.985 Q8GS39 →
P49018 — 0.984 P49018 →
Q8T4E1 — 0.982 Q8T4E1 →
Q9USP5 — 0.980 Q9USP5 →
Q3MHZ7 — 0.979 Q3MHZ7 →
Q5R6L8 — 0.978 Q5R6L8 →
P23613 — 0.978 P23613 →
P57748 — 0.977 P57748 →
MMP14 Matrix metalloproteinase-14 0.977 landscape →