Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261541 | 1.00 | HTT (0.37) | HTTKMT2ALMNAOPRD1TSHR | |
| Hydrochloric Acid SCHEMBL11261315 | 0.98 | HTT (0.36) | HTTKMT2ALMNAOPRD1TSHR | |
| Hydrochloric Acid SCHEMBL11261312 | 0.98 | HTT (0.36) | HTTKMT2ALMNAOPRD1TSHR | |
| Cadaverine Tartrate SCHEMBL11355479 | 0.87 | GRM2 (0.35) | HTTKMT2AGRM2 | |
| Cadaverine Tartrate SCHEMBL11260149 | 0.87 | GRM2 (0.35) | HTTKMT2AGRM2 | |
| Hydrochloric Acid SCHEMBL11261893 | 0.79 | HTR2C (0.33) | — | |
| Hydrochloric Acid SCHEMBL11261909 | 0.79 | HTR2C (0.33) | — | |
| Hydrochloric Acid SCHEMBL11259627 | 0.78 | SIGMAR1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL11261257 | 0.78 | KMT2A (0.37) | HTTKMT2AOPRD1 | |
| Hydrochloric Acid SCHEMBL11261254 | 0.78 | KMT2A (0.37) | HTTKMT2AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315006-A | Benzoxocin derivatives having anxiolytic and anti-convulsant activities | GLAXO GROUP LIMITED (GB) | 1982-02-09 | — | — | US | claimed |
| EP-0024843-A1 | 3,4,5,6-Tetrahydro-2,6-methano-4 beta-amino-1-benzoxocin derivatives, process for their preparation and compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-03-11 | — | — | EP | claimed |
| US-4315006-A | Benzoxocin derivatives having anxiolytic and anti-convulsant activities | GLAXO GROUP LIMITED (GB) | 1982-02-09 | — | — | US | disclosed |
| EP-0024843-A1 | 3,4,5,6-Tetrahydro-2,6-methano-4 beta-amino-1-benzoxocin derivatives, process for their preparation and compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-03-11 | — | — | EP | disclosed |