Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268642 | 1.00 | MAPT (0.45) | MAPTLTB4RNAAASMN1; SMN2TRPA1 | |
| SCHEMBL11261409 | 1.00 | MAPT (0.45) | MAPTLTB4RNAAASMN1; SMN2TRPA1 | |
| SCHEMBL11263275 | 1.00 | MAPT (0.45) | MAPTLTB4RNAAASMN1; SMN2TRPA1 | |
| SCHEMBL11261128 | 0.99 | MAPT (0.46) | MAPTLTB4RNAAASMN1; SMN2TRPA1 | |
| SCHEMBL2673427 | 0.89 | MAPT (0.49) | MAPTSMN1; SMN2 | |
| SCHEMBL10383315 | 0.88 | PPARA (0.48) | — | |
| SCHEMBL11265396 | 0.88 | PPARA (0.48) | — | |
| SCHEMBL11277720 | 0.84 | MEN1 (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL11202434 | 0.83 | TDP1 (0.56) | MAPTLTB4RSMN1; SMN2TRPA1RXFP1 | |
| SCHEMBL10874645 | 0.83 | TDP1 (0.56) | MAPTLTB4RSMN1; SMN2TRPA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |