Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269543 | 0.88 | MAPT (0.39) | MEN1KMT2AMAPTPPARGPPARA | |
| SCHEMBL11261091 | 0.88 | PPARA (0.51) | MAPTPPARGPPARADPP4HSD17B10 | |
| SCHEMBL11261335 | 0.87 | LDHA (0.49) | KMT2AMAPTALOX5ALDH1A1 | |
| SCHEMBL11261128 | 0.85 | MAPT (0.46) | KMT2AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11210888 | 0.84 | MEN1 (0.57) | MEN1KMT2AMAPTMAPK1PPARG | |
| SCHEMBL11261409 | 0.84 | MAPT (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL11268642 | 0.84 | MAPT (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL11263275 | 0.84 | MAPT (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL11261630 | 0.84 | MAPT (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL7708851 | 0.83 | DPP4 (0.40) | MEN1KMT2AMAPTPPARGPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |