Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089771 | 0.81 | PPARA (0.52) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL11094347 | 0.81 | PPARA (0.48) | KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11095134 | 0.80 | PPARG (0.44) | SMN1; SMN2 | |
| SCHEMBL11089623 | 0.80 | PPARA (0.45) | ALDH1A1HPGDKDM4EMAPTRAB9A | |
| SCHEMBL11092025 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4EHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11092116 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL11095117 | 0.79 | LMNA (0.44) | MAPT | |
| SCHEMBL11130558 | 0.77 | PPARA (0.45) | ALDH1A1HPGDKDM4EHTTMAPT | |
| SCHEMBL11098273 | 0.77 | PPARA (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11253558 | 0.76 | HDAC8 (0.45) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351950-A | Anti-arteriosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| EP-0032063-A2 | Novel substituted arylene compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1981-07-15 | — | — | EP | disclosed |