Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261799 | 0.82 | SMN1; SMN2 (0.49) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7056919 | 0.79 | SMN1; SMN2 (0.44) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL11263287 | 0.77 | KMT2A (0.48) | ATMKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11265313 | 0.77 | HPGD (0.42) | KCNMA1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11263124 | 0.73 | KMT2A (0.38) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL17291147 | 0.71 | KMT2A (0.53) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL15811721 | 0.69 | KMT2A (0.61) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL1525273 | 0.68 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL1712790 | 0.68 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL16364505 | 0.68 | PTGS1 (0.60) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |