Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266686 | 0.87 | KMT2A (0.50) | HPGDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11261799 | 0.82 | SMN1; SMN2 (0.49) | HPGDNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL11260852 | 0.80 | OPRM1 (0.46) | HPGDL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7056919 | 0.79 | SMN1; SMN2 (0.44) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11263287 | 0.77 | KMT2A (0.48) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11261892 | 0.77 | CYP1A1 (0.40) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11270499 | 0.73 | MEN1 (0.44) | HPGDL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11263124 | 0.73 | KMT2A (0.38) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17291147 | 0.71 | KMT2A (0.53) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL661853 | 0.70 | KMT2A (0.48) | HPGDNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |