Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300503 | 0.92 | PPARA (0.49) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11263047 | 0.92 | PPARA (0.46) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11267723 | 0.91 | PPARA (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11255456 | 0.91 | CYP1A2 (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11290711 | 0.90 | PPARA (0.47) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11302417 | 0.90 | PPARA (0.47) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11266988 | 0.90 | PPARA (0.51) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11256466 | 0.89 | PPARA (0.56) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11269616 | 0.88 | PPARA (0.44) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11252541 | 0.87 | PPARA (0.53) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |