Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302417 | 0.98 | PPARA (0.47) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11262074 | 0.92 | PPARA (0.59) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11303888 | 0.86 | PPARA (0.43) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11259223 | 0.84 | PPARA (0.52) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11249945 | 0.84 | PPARA (0.52) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11263047 | 0.84 | PPARA (0.46) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11252541 | 0.84 | PPARA (0.53) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11256466 | 0.83 | PPARA (0.56) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11255456 | 0.83 | CYP1A2 (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11267723 | 0.83 | PPARA (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015523-B1 | INDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR MEDICAMENTS | Dr. Karl Thomae GmbH (DE) | 1982-10-13 | — | — | EP | disclosed |