Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13592714 | 1.00 | MAPT (0.45) | MAPTAPPHTTMEN1KMT2A | |
| SCHEMBL13591490 | 1.00 | MAPT (0.45) | MAPTAPPHTTMEN1KMT2A | |
| SCHEMBL16696032 | 1.00 | MAPT (0.45) | MAPTAPPHTTMEN1KMT2A | |
| SCHEMBL20253062 | 1.00 | MAPT (0.45) | MAPTAPPHTTMEN1KMT2A | |
| SCHEMBL13365118 | 1.00 | MAPT (0.45) | MAPTAPPHTTMEN1KMT2A | |
| Iodide SCHEMBL21314819 | 0.98 | MAPT (0.47) | MAPTAPPHTTMEN1KMT2A | |
| Bromide SCHEMBL18301315 | 0.98 | MAPT (0.44) | MAPTAPPHTTMEN1KMT2A | |
| Perchlorate SCHEMBL3631533 | 0.94 | MAPT (0.42) | MAPTAPPHTTMEN1KMT2A | |
| Perchlorate SCHEMBL1405631 | 0.94 | MAPT (0.42) | MAPTAPPHTTMEN1KMT2A | |
| SCHEMBL6870013 | 0.94 | MAPT (0.50) | MAPTAPPHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-8834846-B2 | Fluorescent NIRF activatable probes for disease detection | BRUKER BIOSPIN CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | BRUKER BIOSPIN CORPORATION | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | LASP1, LSS, SELL | MAPT 1897/4885APP 3689/4885HTT 2631/4885 |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | CTSF, ENGASE, DNTT | MAPT 1543/4885APP 617/4885HTT 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.