CTSF — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2953108	1.00	18/20
SCHEMBL3759357	1.00	18/20
SCHEMBL2951583	0.84	17/20
SCHEMBL2155109	0.83	17/20
SCHEMBL3760063	0.84	16/20
SCHEMBL2925461	0.74	16/20
SCHEMBL3760635	1.00	15/20
SCHEMBL3760637	1.00	15/20
SCHEMBL3760645	1.00	15/20
SCHEMBL2926229	0.82	15/20
SCHEMBL2926231	0.82	15/20
SCHEMBL2926232	0.82	15/20
SCHEMBL3138544	0.68	15/20
SCHEMBL2156856	0.88	14/20
SCHEMBL2926034	0.83	14/20
SCHEMBL2926037	0.83	14/20
SCHEMBL2926040	0.83	14/20
SCHEMBL2927165	0.79	14/20
SCHEMBL2922410	0.56	14/20
SCHEMBL2944796	0.87	13/20

Clinical trials — most relevant to CTSF by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation	PHASE4	COMPLETED
Efficacy and Safety of Favipiravir and Ribavirin Formulation for Treatment of COVID-19	PHASE2/PHASE3	UNKNOWN
Sterile Amniotic Fluid Filtrate Epidural Injection.	PHASE1/PHASE2	COMPLETED
The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism	EARLY_PHASE1	UNKNOWN
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis	nan	COMPLETED
Diagnostic Value of Serum Cathepsin S and Chromogranin A in DKD	nan	NOT_YET_RECRUITING
Usefulness of the Variation of the CLIF-C ACLF Score in Patients With Acute on Chronic Liver Failure	nan	UNKNOWN
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients	nan	RECRUITING
Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients	nan	COMPLETED
Predicting Pancreatic Necrosis Using mitDNA	nan	UNKNOWN
The Role of Vitamin K2 in Preventing Glucocorticoid-Induced Bone Loss in Children With Nephrotic Syndrome	nan	RECRUITING
Synovial Fluid Bank From Arthritic Patients	nan	RECRUITING
Circulating Markers for Ischemic Heart Disease	nan	RECRUITING
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Proteases in Patients With Prostate Cancer That Has Spread to the Bone	nan	COMPLETED
Chemokine Mechanisms in Chronic Pelvic Pain	nan	COMPLETED
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study	nan	RECRUITING
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease	nan	UNKNOWN
Fasting, Exercise, and Diet to Activate Autophagy in Depression	nan	NOT_YET_RECRUITING
Screening of Lysosomal Storage Disorders Diseases in Minority Groups	nan	UNKNOWN
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Acute Pancreatitis Targets (APT) Study	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study	nan	NOT_YET_RECRUITING
Utility of Presepsin in Children Sepsis	nan	UNKNOWN
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Disorders of the Acute Phase Response Following Trauma and Invasive Surgery	nan	ENROLLING_BY_INVITATION
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a CTSF binder may also engage these)

Protein	Name	Similarity
Q9R013	—	1.000	Q9R013 →
P56202	—	0.989	P56202 →
P56203	—	0.988	P56203 →
Q9TST1	—	0.986	Q9TST1 →
O46427	—	0.981	O46427 →
Q3T0I2	—	0.978	Q3T0I2 →
Q8VYS0	—	0.977	Q8VYS0 →
CTSH	Pro-cathepsin H	0.977	landscape →
P49935	—	0.977	P49935 →
Q96SM3	—	0.977	Q96SM3 →
Q5RB02	—	0.976	Q5RB02 →
Q80YC5	—	0.976	Q80YC5 →
Q07104	—	0.976	Q07104 →
F7	Coagulation factor VII	0.976	landscape →
LOXL3	Lysyl oxidase homolog 3	0.975	landscape →
Q3U435	—	0.975	Q3U435 →
Q9Z1W4	—	0.975	Q9Z1W4 →
O97507	—	0.974	O97507 →
P00743	—	0.974	P00743 →
Q2F9P2	—	0.974	Q2F9P2 →
P23276	—	0.974	P23276 →
D3ZTE0	—	0.974	D3ZTE0 →
Q9Z100	—	0.974	Q9Z100 →
Q499S5	—	0.974	Q499S5 →
Q8BM88	—	0.973	Q8BM88 →
CTSC	Dipeptidyl peptidase 1	0.973	landscape →
Q9VN93	—	0.973	Q9VN93 →
Q9Z217	—	0.973	Q9Z217 →
A0A286YEC0	—	0.973	A0A286YEC0 →
Q924C6	—	0.972	Q924C6 →