Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259227 | 0.87 | THRB (0.35) | HTR2CTHRBMAPTLMNATP53 | |
| SCHEMBL11262366 | 0.86 | HTR2C (0.34) | HTR2CMAPTLMNATP53KMT2A | |
| SCHEMBL11271216 | 0.86 | HTR2C (0.34) | HTR2CLMNATP53KMT2AMEN1 | |
| SCHEMBL11269299 | 0.84 | HTR2C (0.33) | HTR2CLMNATP53KMT2AMEN1 | |
| SCHEMBL11269416 | 0.82 | KMT2A (0.38) | HTR2CMAPTTP53KMT2AMEN1 | |
| SCHEMBL11256677 | 0.81 | HTR2C (0.42) | HTR2CMAPTLMNATP53KMT2A | |
| SCHEMBL11262591 | 0.80 | TP53 (0.32) | TP53 | |
| SCHEMBL11269352 | 0.78 | TP53 (0.34) | HTR2CMAPTTP53KMT2AMEN1 | |
| SCHEMBL11271742 | 0.77 | — | — | |
| SCHEMBL11262762 | 0.76 | HTR2C (0.35) | HTR2CTP53KMT2AMEN1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | claimed |
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |