Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11254022 | 0.99 | RAD52 (0.41) | HTR2CRAD52RAB9ANPC1TSHR | |
| SCHEMBL11265320 | 0.99 | HTR2C (0.41) | HTR2CRAD52RAB9ANPC1TSHR | |
| SCHEMBL11260549 | 0.89 | HTR2C (0.36) | HTR2CRAD52RAB9ANPC1TSHR | |
| SCHEMBL11257441 | 0.88 | HTR2C (0.39) | HTR2CRAD52RAB9ANPC1HDAC6 | |
| SCHEMBL11265827 | 0.88 | HTR2C (0.39) | HTR2CRAD52RAB9ANPC1TSHR | |
| SCHEMBL11251027 | 0.86 | HTR2C (0.39) | HTR2CRAD52RAB9ANPC1HDAC6 | |
| SCHEMBL11254903 | 0.86 | NPC1 (0.43) | HTR2CRAD52RAB9ANPC1TSHR | |
| SCHEMBL11256981 | 0.85 | SMN1; SMN2 (0.41) | HTR2CRAD52RAB9ANPC1HDAC6 | |
| SCHEMBL11258507 | 0.84 | SMN1; SMN2 (0.39) | HTR2CRAD52RAB9ANPC1TSHR | |
| SCHEMBL11260544 | 0.82 | HTT (0.42) | RAB9ANPC1TSHRSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | claimed |
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |