Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257677 | 0.94 | DRD2 (0.40) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| Water SCHEMBL11255617 | 0.93 | DRD2 (0.39) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11256981 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11265320 | 0.85 | HTR2C (0.41) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11262480 | 0.84 | HTR2C (0.40) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11254022 | 0.83 | RAD52 (0.41) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11256220 | 0.80 | EPHX2 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL11257441 | 0.78 | HTR2C (0.39) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11265827 | 0.78 | HTR2C (0.39) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11258040 | 0.78 | OPRM1 (0.37) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |