Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258195 | 0.92 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| Bromide SCHEMBL11265180 | 0.91 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| Bromide SCHEMBL11247155 | 0.91 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| SCHEMBL11191207 | 0.89 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| SCHEMBL11191206 | 0.89 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| SCHEMBL11194278 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| SCHEMBL11194276 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| SCHEMBL11246210 | 0.87 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3DRD2OPRM1 | |
| SCHEMBL11249000 | 0.86 | SLC6A4 (0.79) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL11248997 | 0.86 | SLC6A4 (0.79) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |