Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | CATSPER1 | Q8NEC5 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715180 | 0.86 | SRD5A2 (0.44) | MAPTPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL11708941 | 0.86 | MAPT (0.48) | MAPTGAAPOLBALDH1A1MAP2K3 | |
| Hydrochloric Acid SCHEMBL11708500 | 0.84 | MAPT (0.47) | MAPTGAAPOLBALDH1A1MAP2K3 | |
| SCHEMBL11720745 | 0.84 | PARP1 (0.49) | MAPTPOLBALDH1A1KMT2ACCNA2 | |
| SCHEMBL11826036 | 0.82 | ALDH1A1 (0.50) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11272310 | 0.80 | RECQL (0.55) | GAAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL11716772 | 0.80 | MAPT (0.43) | MAPTGAAPOLBALDH1A1HTT | |
| SCHEMBL536092 | 0.80 | TDP1 (0.42) | MAPTGAAPOLBALDH1A1MAP2K3 | |
| SCHEMBL11834773 | 0.79 | ALDH1A1 (0.43) | MAPTGAAPOLBALDH1A1HPGD | |
| SCHEMBL11713185 | 0.79 | MAPT (0.46) | MAPTGAAPOLBALDH1A1MAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31071-E | 6-Aza-3H-1,4-benzodiazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4012397-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-03-15 | — | — | US | disclosed |
| US-4008223-A | SPASMOLYTIC, ANTIPHLOGISTIC, TRANQUILIZER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-02-15 | — | — | US | disclosed |
| US-3972873-A | Certain pyrido[3,2-e]1,4-diazepinones and derivatives | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3969361-A | 2-Benzoyl-3-amino-pyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-07-13 | — | — | US | disclosed |