SCHEMBL11263233

SCHEMBL11263233

C1CC[C@@H](O[C@@H]2CCCCO2)OC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28813769 1.00 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL30805 1.00 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL10644184 0.97 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL4260336 0.97 MEN1 (0.33) MEN1KMT2AKDM4C
SCHEMBL79345 0.91 NOS2 (0.33)
SCHEMBL9785228 0.87 OSBP (0.33) MEN1KMT2AKDM4C
SCHEMBL16411045 0.87 OSBP (0.33) MEN1KMT2AKDM4C
Benzene SCHEMBL9215722 0.86 MEN1 (0.38) MEN1KMT2AKDM4C
SCHEMBL2330280 0.85 OSBP (0.32) MEN1KMT2A
SCHEMBL25162744 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005889-B1 PROCESS FOR THE PREPARATION OF BETA-LACTAM DERIVATIVES, THE NOVEL DERIVATIVES SO OBTAINABLE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Technobiotic Ltd. (CH) 1982-06-16 EP disclosed
US-4283531-A Synthesis of β-lactams having a substituted hydroxymethylene group at the position α to the lactam carbonyl group SCHERING CORPORATION (US) 1981-08-11 US disclosed
US-4272439-A 6-(Substituted-hydroxymethylene penams) SCHERING CORPORATION (US) 1981-06-09 US disclosed
EP-0005889-A1 Process for the preparation of beta-lactam derivatives, the novel derivatives so obtainable and pharmaceutical compositions containing them Technobiotic Ltd. (CH) 1979-12-12 EP disclosed