Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280423 | 0.91 | HTT (0.68) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11275070 | 0.91 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11275574 | 0.88 | HTT (0.70) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11482857 | 0.88 | HTT (0.59) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11266871 | 0.88 | HTT (0.59) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11279295 | 0.85 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11273237 | 0.81 | HTT (0.49) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11302866 | 0.78 | HRH4 (0.47) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11490245 | 0.78 | HTT (0.58) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11271385 | 0.77 | HTT (0.46) | HTTSMN1; SMN2MAPTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |