Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263264 | 0.88 | HTT (0.75) | HTTSMN1; SMN2POLBPKMMAPT | |
| SCHEMBL11482857 | 0.87 | HTT (0.59) | HTTSMN1; SMN2POLBPKMMAPT | |
| SCHEMBL11280423 | 0.83 | HTT (0.68) | HTTSMN1; SMN2POLBPKMMAPT | |
| SCHEMBL11275070 | 0.82 | HTT (0.71) | HTTSMN1; SMN2FBP1POLBPKM | |
| SCHEMBL11275574 | 0.82 | HTT (0.70) | HTTSMN1; SMN2POLBPKMMAPT | |
| SCHEMBL11273503 | 0.78 | HTT (0.46) | HTTSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL11279295 | 0.77 | HTT (0.71) | HTTSMN1; SMN2FBP1POLBPKM | |
| SCHEMBL11273237 | 0.76 | HTT (0.49) | HTTSMN1; SMN2POLBPKMMAPT | |
| SCHEMBL11302866 | 0.74 | HRH4 (0.47) | HTTSMN1; SMN2POLBPKMMAPT | |
| SCHEMBL10220436 | 0.73 | HRH4 (0.48) | SMN1; SMN2FBP1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |