Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10944103 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28458432 | 0.97 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL73306 | 0.96 | — | — | |
| Bromide SCHEMBL28411345 | 0.93 | — | — | |
| Ethylene Glycol SCHEMBL9246579 | 0.87 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL11791294 | 0.80 | — | — | |
| SCHEMBL6684911 | 0.80 | — | — | |
| SCHEMBL6314222 | 0.80 | BACE1 (0.36) | — | |
| SCHEMBL6314225 | 0.80 | BACE1 (0.36) | — | |
| SCHEMBL12558778 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141386-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2009-11-26 | — | — | WO | disclosed |
| EP-0423087-A2 | Mixed lithium amides and reagent compositions thereof | CYPRUS FOOTE MINERAL COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4235908-A | 4-Aminoquinoline derivatives, useful as anti-inflammatory agents | JOHN WYETH & BROTHER LIMITED (GB) | 1980-11-25 | — | — | US | disclosed |
| EP-0001175-A1 | 4-Aminoquinoline derivatives, a process for their preparation and pharmaceutical compositions containing them | JOHN WYETH & BROTHER LIMITED (GB) | 1979-03-21 | — | — | EP | disclosed |