Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 8/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256198 | 0.98 | NCF1 (0.53) | NCF1FGFR1TAAR1LTA4HPLA2G2A | |
| Hydrochloric Acid SCHEMBL11262673 | 0.96 | NCF1 (0.51) | NCF1FGFR1TAAR1LTA4HPLA2G2A | |
| Hydrochloric Acid SCHEMBL11374329 | 0.96 | NCF1 (0.51) | NCF1FGFR1TAAR1LTA4HPLA2G2A | |
| Hydrochloric Acid SCHEMBL11262065 | 0.86 | NCF1 (0.49) | NCF1MAPTAGXT | |
| SCHEMBL23452963 | 0.82 | NCF1 (0.76) | NCF1 | |
| SCHEMBL11263550 | 0.81 | NCF1 (0.42) | NCF1FGFR1TAAR1LTA4HPLA2G2A | |
| SCHEMBL9828364 | 0.79 | NCF1 (0.49) | NCF1MAPTMEN1F2LMNA | |
| Hydrochloric Acid SCHEMBL10728763 | 0.78 | NCF1 (0.47) | NCF1MAPTMEN1F2LMNA | |
| Hydrochloric Acid SCHEMBL9828267 | 0.78 | NCF1 (0.47) | NCF1MAPTMEN1F2LMNA | |
| SCHEMBL23453148 | 0.77 | NCF1 (0.77) | NCF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314061-A | Certain 3,6-bis-(heteroaminoalkoxy) acridines | AMERICAN CYANAMID COMPANY | 1982-02-02 | — | — | US | disclosed |
| EP-0031407-A1 | Substituted 3,6 bis-(aminoalkoxy)acridines, and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1981-07-08 | — | — | EP | disclosed |