Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29215803 | 0.87 | POLB (0.46) | ALDH1A1POLBLMNAMAPTGAA | |
| SCHEMBL9243144 | 0.86 | POLB (0.36) | ALDH1A1HSD17B10POLBLMNAMAPT | |
| SCHEMBL10844145 | 0.86 | POLB (0.36) | ALDH1A1HSD17B10POLBLMNAMAPT | |
| SCHEMBL729517 | 0.82 | POLB (0.57) | ALDH1A1HSD17B10POLBLMNAMAPT | |
| SCHEMBL1807695 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HSD17B10POLBLMNAMAPT | |
| SCHEMBL27417200 | 0.80 | POLB (0.32) | ALDH1A1POLBLMNAHTTTDP1 | |
| SCHEMBL1807698 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HSD17B10POLBLMNAMAPT | |
| SCHEMBL1607817 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSD17B10LMNAMAPTGAA | |
| SCHEMBL10596213 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSD17B10LMNAMAPTGAA | |
| SCHEMBL1807548 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003883-B1 | AMINO-DIBENZOPYRANS, THEIR PREPARATION, FORMULATIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS | ELI LILLY AND COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |
| US-4195025-A | 9-Amino-dibenzopyrans | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0003883-A1 | Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals | ELI LILLY AND COMPANY (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4152450-A | 9-Amino-dibenzopyrans | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |