SCHEMBL11264047

SCHEMBL11264047

NCCCCC(=O)c1ccc(CCC(N)=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.47
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
F2 P00734 1/20 0.44
F10 P00742 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 1/20 0.43
THRA P10827 2/20 0.42
THRB P10828 2/20 0.42
HSD17B3 P37058 6/20 0.41
CAPN1 P07384 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11133258 0.98 DPP4 (0.46) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11135374 0.98 DPP4 (0.46) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11134116 0.87 L3MBTL1 (0.54) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11133284 0.85 HDAC3 (0.54) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11134216 0.85 HDAC3 (0.54) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11134102 0.85 HDAC3 (0.54) DPP4NPC1RAB9ATDP1CASP3
Hydrochloric Acid SCHEMBL11134492 0.84 HDAC3 (0.53) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11133673 0.83 L3MBTL1 (0.47) NPC1RAB9ATDP1L3MBTL1LMNA
SCHEMBL11267102 0.83 DPP4 (0.51) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL11131939 0.82 HRH1 (0.50) LMNAMAPTCAPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044541-A1 Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds TEIJIN LIMITED (JP) 1982-01-27 EP disclosed