Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263636 | 0.96 | PPARA (0.47) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11265169 | 0.90 | KDM4E (0.50) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11259439 | 0.90 | KDM4E (0.45) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11249945 | 0.88 | PPARA (0.52) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11259223 | 0.88 | PPARA (0.52) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11267723 | 0.87 | PPARA (0.45) | HSD17B10PPARAKMT2APPARGABCB11 | |
| SCHEMBL11269239 | 0.86 | KMT2A (0.47) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11256466 | 0.85 | PPARA (0.56) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11249243 | 0.83 | PPARA (0.42) | KDM4EHSD17B10PPARAKMT2APPARG | |
| SCHEMBL11263047 | 0.80 | PPARA (0.46) | KDM4EHSD17B10PPARAKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |