Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256466 | 0.91 | PPARA (0.56) | KMT2AKDM4EHSD17B10PTGDR2TSHR | |
| SCHEMBL11263543 | 0.90 | KDM4E (0.49) | KMT2AKDM4EHSD17B10CNR2PTGDR2 | |
| SCHEMBL11249243 | 0.89 | PPARA (0.42) | KMT2AKDM4EHSD17B10CNR2TSHR | |
| SCHEMBL11255456 | 0.89 | CYP1A2 (0.45) | KMT2AKDM4EHSD17B10TSHRPPARA | |
| SCHEMBL11264117 | 0.86 | KDM4E (0.46) | KMT2AKDM4EHSD17B10CNR2PTGDR2 | |
| SCHEMBL11252371 | 0.86 | GRIK2 (0.56) | KMT2AKDM4EHSD17B10TSHRPPARA | |
| SCHEMBL11256650 | 0.85 | PPARA (0.42) | KMT2AKDM4EHSD17B10CNR2TSHR | |
| SCHEMBL11263636 | 0.85 | PPARA (0.47) | KMT2AKDM4EHSD17B10CNR2TSHR | |
| SCHEMBL11249945 | 0.84 | PPARA (0.52) | KMT2AKDM4EHSD17B10CNR2TSHR | |
| SCHEMBL11259223 | 0.84 | PPARA (0.52) | KMT2AKDM4EHSD17B10CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |