Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274624 | 0.90 | KMT2A (0.55) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL11277772 | 0.89 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11418845 | 0.86 | KMT2A (0.55) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL11277920 | 0.85 | KLK7 (0.47) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL11280076 | 0.85 | SMN1; SMN2 (0.48) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL16383778 | 0.84 | KLK7 (0.46) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| Camostat SCHEMBL8829828 | 0.84 | PRSS1 (0.66) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL16355694 | 0.83 | PRSS1 (0.49) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| Camostat SCHEMBL125269 | 0.83 | PRSS1 (0.68) | KLK7SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL20008640 | 0.83 | PRSS1 (0.68) | KLK7SMN1; SMN2NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |