Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264175 | 0.89 | KLK7 (0.60) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL11277441 | 0.88 | HPGD (0.58) | MEN1KMT2AMAPTGAATSHR | |
| SCHEMBL11274623 | 0.87 | RECQL (0.49) | MEN1KMT2AMAPTUSP2GAA | |
| SCHEMBL11274624 | 0.87 | KMT2A (0.55) | MEN1KMT2AMAPTUSP2GAA | |
| SCHEMBL1648216 | 0.87 | KMT2A (0.47) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL11275962 | 0.86 | KMT2A (0.59) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL11275960 | 0.86 | KMT2A (0.59) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL4104661 | 0.85 | KMT2A (0.59) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10309162 | 0.85 | KMT2A (0.63) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29825181 | 0.83 | KMT2A (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |