SCHEMBL11264298

SCHEMBL11264298

CCOC1CCC(COC2CCC(c3ccccc3)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 15/20 0.46
DRD2 P14416 1/20 0.41
IDO1 P14902 1/20 0.41
GPR119 Q8TDV5 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11264295 1.00 HCRTR2 (0.46) HCRTR2DRD2IDO1GPR119
SCHEMBL18361625 0.90 DRD2 (0.49) HCRTR2DRD2
SCHEMBL11258689 0.89 CYP2C9 (0.47) HCRTR2DRD2GPR119
SCHEMBL11258692 0.89 CYP2C9 (0.47) HCRTR2DRD2GPR119
SCHEMBL11260150 0.87 HCRTR2 (0.42) HCRTR2DRD2GPR119
SCHEMBL11260153 0.87 HCRTR2 (0.42) HCRTR2DRD2GPR119
SCHEMBL11253813 0.86 HCRTR2 (0.41) HCRTR2DRD2GPR119
SCHEMBL11253811 0.86 HCRTR2 (0.41) HCRTR2DRD2GPR119
SCHEMBL11269066 0.84 HCRTR2 (0.41) HCRTR2DRD2GPR119
SCHEMBL11269085 0.84 HCRTR2 (0.41) HCRTR2DRD2GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4361494-A Anisotropic cyclohexyl cyclohexylmethyl ethers BBC BROWN, BOVERI, & COMPANY, LIMITED (CH) 1982-11-30 US disclosed