Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261787 | 0.82 | HTR2A (0.37) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL11272693 | 0.82 | HTR2A (0.31) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL11280825 | 0.77 | HTR2C (0.38) | HTR2C | |
| SCHEMBL11270655 | 0.74 | HTR2A (0.32) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL11262097 | 0.72 | HTR2C (0.39) | HTR2AHTR2CMEN1CYP1A2CASP1 | |
| SCHEMBL11278308 | 0.71 | ERN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL11269902 | 0.71 | HTR2C (0.38) | HTR2AHTR2CMEN1CYP1A2CASP1 | |
| SCHEMBL11275878 | 0.71 | — | — | |
| SCHEMBL11261985 | 0.69 | SMN1; SMN2 (0.40) | PKMMEN1CYP2C19KMT2A | |
| SCHEMBL11273824 | 0.69 | HTR2A (0.43) | HTR2AHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |