Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272551 | 0.84 | MAPT (0.30) | MAPT | |
| SCHEMBL11262598 | 0.82 | AKR1B1 (0.33) | ALDH1A1MAPTMAPK1KDM4EL3MBTL1 | |
| SCHEMBL11270748 | 0.73 | MAPT (0.35) | SMN1; SMN2ALDH1A1TDP1HIF1AMAPT | |
| SCHEMBL11273833 | 0.72 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1MAPTALOX12L3MBTL1 | |
| SCHEMBL11264935 | 0.72 | ESPL1 (0.34) | ALDH1A1CYP3A4HIF1AMAPTMEN1 | |
| SCHEMBL11273824 | 0.72 | HTR2A (0.43) | ALDH1A1MAPTMAPK1KDM4EL3MBTL1 | |
| SCHEMBL11260482 | 0.72 | ALDH1A1 (0.36) | ALDH1A1CYP3A4TSHRHPGDMAPT | |
| SCHEMBL11272587 | 0.71 | MAPT (0.35) | ALDH1A1CYP3A4TSHRMAPTMAPK1 | |
| SCHEMBL11264369 | 0.69 | HTR2A (0.35) | MEN1KMT2ACYP2C19PKM | |
| SCHEMBL11266402 | 0.68 | MAPT (0.36) | ALDH1A1TDP1TSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |