Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668707 | 0.86 | MAPT (0.47) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL12196693 | 0.86 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL27675236 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL19193182 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL16147601 | 0.83 | TSHR (0.46) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL10478090 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL28961928 | 0.80 | TSHR (0.50) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL27759231 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL10959235 | 0.80 | TSHR (0.55) | MAPTALDH1A1CYP3A4KAT2BKMT2A | |
| SCHEMBL16011445 | 0.79 | CYP1A2 (0.45) | MAPTALDH1A1KDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284178-A2 | Inhibitors of cancer cell, T-cell and keratinocyte proliferation | 4SC AG (DE) | 2011-02-16 | — | — | EP | disclosed |