SCHEMBL11264529

SCHEMBL11264529

CCCN(CCC)C(=O)N(C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.52
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
GLA P06280 1/20 0.48
EGFR P00533 1/20 0.43
ERBB2 P04626 1/20 0.43
KMT2A Q03164 3/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
P2RX1 P51575 1/20 0.41
P2RX3 P56373 1/20 0.41
P2RX4 Q99571 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11121083 0.89 GAA (0.49) TP53ALDH1A1TSHRGLANPSR1
SCHEMBL14200304 0.89 TP53 (0.42) TP53ALDH1A1TSHRGLAEGFR
SCHEMBL11278575 0.88 TACR1 (0.54) TP53ALDH1A1TSHRGLANPC1
SCHEMBL25230065 0.86 NPC1 (0.54) NPC1RAB9A
SCHEMBL11264858 0.86 NPC1 (0.54) NPC1RAB9A
SCHEMBL11268083 0.85 ALDH1A1 (0.57) ALDH1A1TSHRGLAKMT2APOLB
SCHEMBL11272838 0.84 ALDH1A1 (0.42) TP53ALDH1A1TSHREGFRERBB2
SCHEMBL14200305 0.80 GAA (0.42) TP53ALDH1A1TSHRGLAKMT2A
SCHEMBL25277619 0.80 ALDH1A1 (0.72) TP53ALDH1A1TSHRGLAKMT2A
SCHEMBL320116 0.80 POLB (0.59) ALDH1A1TSHRGLAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
US-4349526-A TRI-SUBSTITUTED PHENYLUREAS AS SOLVENT IN ANTHRAQUINONE PROCESS DEGUSSA AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed