SCHEMBL11264682

SCHEMBL11264682

CN(C)CCCCOc1ccccc1CCc1ccccc1Cl

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.58
HRH1 P35367 1/20 0.55
HRH3 Q9Y5N1 1/20 0.53
HTR1B P28222 1/20 0.52
KDM4E B2RXH2 1/20 0.50
DRD2 P14416 1/20 0.49
DRD1 P21728 1/20 0.49
DRD4 P21917 1/20 0.49
DRD5 P21918 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11258745 0.99 TAAR1 (0.57) TAAR1HRH1HRH3HTR1BKDM4E
SCHEMBL11269198 0.99 TAAR1 (0.57) TAAR1HRH1HRH3HTR1BKDM4E
SCHEMBL11250748 0.95 HRH1 (0.60) TAAR1HRH1HRH3HTR1BDRD2
SCHEMBL11260050 0.91 TAAR1 (0.62) TAAR1HRH1HRH3HTR1BDRD2
SCHEMBL11259613 0.88 HRH1 (0.49) HRH1HRH3HTR1BKDM4E
SCHEMBL11262970 0.85 HRH1 (0.57) HRH1HTR1BDRD2DRD1DRD4
SCHEMBL11259882 0.85 HRH1 (0.57) HRH1HTR1BKDM4EDRD2DRD1
SCHEMBL11259238 0.85 HRH1 (0.55) HRH1HTR1BDRD2DRD1DRD4
SCHEMBL11253611 0.84 HRH1 (0.68) HRH1DRD2DRD1DRD4DRD5
SCHEMBL11262056 0.84 HRH1 (0.60) HRH1HTR1BKDM4EDRD2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323568-A INHIBIT PLATELET AGGREGATION MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1982-04-06 US disclosed
EP-0001759-B1 (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES MITSUBISHI KASEI CORPORATION (JP) 1981-12-30 EP disclosed
US-4220603-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1980-09-02 US disclosed
EP-0001759-A1 (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances MITSUBISHI KASEI CORPORATION (JP) 1979-05-16 EP disclosed