Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | DRD5 | P21918 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250748 | 0.92 | HRH1 (0.60) | TAAR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11264682 | 0.91 | TAAR1 (0.58) | TAAR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11269198 | 0.90 | TAAR1 (0.57) | TAAR1DRD2DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL11258745 | 0.90 | TAAR1 (0.57) | TAAR1HRH1HTR1BHRH3KCNH2 | |
| SCHEMBL11255685 | 0.87 | DRD2 (0.52) | TAAR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11257616 | 0.84 | HTR7 (0.66) | TAAR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11260586 | 0.84 | DRD2 (0.58) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL11245170 | 0.83 | DRD2 (0.55) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL11244476 | 0.83 | DRD2 (0.74) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL11266289 | 0.81 | DRD2 (0.59) | DRD2DRD1DRD4DRD5HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |