Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545561 | 0.89 | MAPT (0.40) | MAPTRECQLALDH1A1GAARAB9A | |
| SCHEMBL8545559 | 0.89 | MAPT (0.40) | MAPTRECQLALDH1A1GAARAB9A | |
| SCHEMBL30999026 | 0.85 | ALDH1A1 (0.38) | MAPTALDH1A1GAARAB9APOLB | |
| SCHEMBL3940169 | 0.83 | TSHR (0.43) | TSHRMAPTRECQLALDH1A1GAA | |
| SCHEMBL17075159 | 0.73 | TSHR (0.41) | TSHRMAPTRECQLALDH1A1GAA | |
| SCHEMBL30420160 | 0.73 | ALDH1A1 (0.40) | MAPTRECQLALDH1A1GAARAB9A | |
| SCHEMBL22213865 | 0.73 | ALDH1A1 (0.40) | MAPTRECQLALDH1A1GAARAB9A | |
| SCHEMBL2914885 | 0.73 | ALDH1A1 (0.46) | TSHRMAPTALDH1A1GAALMNA | |
| SCHEMBL72855 | 0.72 | MAPT (0.51) | TSHRMAPTALDH1A1LMNAPOLB | |
| SCHEMBL16059991 | 0.71 | TSHR (0.39) | TSHRMAPTRECQLALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |