Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264141 | 0.92 | HTR2C (0.43) | DRD2DRD4DRD3SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11255073 | 0.91 | RAD52 (0.44) | SMN1; SMN2ALDH1A1TP53HTR2CRAD52 | |
| SCHEMBL11259076 | 0.90 | SMN1; SMN2 (0.41) | DRD2DRD4DRD3SMN1; SMN2CYP3A4 | |
| SCHEMBL11256677 | 0.82 | HTR2C (0.42) | SMN1; SMN2ALDH1A1TP53HTR2CRAD52 | |
| SCHEMBL11262762 | 0.76 | HTR2C (0.35) | TP53HTR2CRAD52RAB9AGAA | |
| SCHEMBL11254540 | 0.74 | HTR2C (0.45) | SMN1; SMN2ALDH1A1TP53TSHRHTR2C | |
| SCHEMBL11253928 | 0.71 | HTR2C (0.40) | SMN1; SMN2ALDH1A1TP53TSHRHTR2C | |
| SCHEMBL11271216 | 0.70 | HTR2C (0.34) | TP53HTR2CRAD52 | |
| SCHEMBL11256191 | 0.70 | HDAC6 (0.38) | SMN1; SMN2ALDH1A1TP53HTR2CRAD52 | |
| SCHEMBL11260549 | 0.69 | HTR2C (0.36) | TSHRHTR2CRAD52RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |