Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11255073 | 0.99 | RAD52 (0.44) | HTR2CRAD52HDAC6NPC1RAB9A | |
| SCHEMBL11264978 | 0.92 | DRD2 (0.44) | HTR2CRAD52NPC1RAB9AALDH1A1 | |
| SCHEMBL11256677 | 0.88 | HTR2C (0.42) | HTR2CRAD52HDAC6NPC1RAB9A | |
| SCHEMBL11262762 | 0.82 | HTR2C (0.35) | HTR2CRAD52RAB9ATP53KMT2A | |
| SCHEMBL11259076 | 0.81 | SMN1; SMN2 (0.41) | HTR2CRAD52NPC1RAB9AALDH1A1 | |
| SCHEMBL11254540 | 0.80 | HTR2C (0.45) | HTR2CRAD52HDAC6NPC1RAB9A | |
| SCHEMBL11253928 | 0.77 | HTR2C (0.40) | HTR2CRAD52HDAC6NPC1RAB9A | |
| SCHEMBL11256191 | 0.75 | HDAC6 (0.38) | HTR2CRAD52HDAC6NPC1RAB9A | |
| SCHEMBL11260549 | 0.75 | HTR2C (0.36) | HTR2CRAD52HDAC6NPC1RAB9A | |
| SCHEMBL11255674 | 0.75 | CASP2 (0.49) | NPC1RAB9AALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |