Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL11179507 | 1.00 | LMNA (0.40) | LMNATP53ALDH1A1CYP2C19TSHR | |
| SCHEMBL27593458 | 0.94 | — | — | |
| SCHEMBL10955651 | 0.76 | TP53 (0.36) | LMNATP53ALDH1A1TSHRSLC7A5 | |
| SCHEMBL3889632 | 0.74 | — | — | |
| SCHEMBL16160077 | 0.72 | TP53 (0.38) | LMNATP53ALDH1A1TSHRSLC7A5 | |
| SCHEMBL28264066 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL808733 | 0.70 | TP53 (0.38) | LMNATP53ALDH1A1TSHRSLC7A5 | |
| SCHEMBL2686145 | 0.69 | TP53 (0.47) | LMNATP53ALDH1A1TSHRSLC7A5 | |
| Carbon Tetrachloride SCHEMBL29008316 | 0.69 | FFAR3 (0.50) | LMNATP53ALDH1A1TSHR | |
| Carbon Tetrachloride SCHEMBL11356447 | 0.69 | FFAR3 (0.50) | LMNATP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000500-B1 | CEPHALOSPRIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1982-04-28 | — | — | EP | disclosed |
| EP-0016900-A1 | Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use | CIBA-GEIGY AG (CH) | 1980-10-15 | — | — | EP | disclosed |
| EP-0000500-A2 | Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |